abstract：BACKGROUND:Metachronous malignancy is also found in the lung cancer population and may be identified before or after diagnosis of lung cancer. No prior studies have documented lung cancer patients with metachronous malignancy and its survival impact in this population. The aim of this study was to try to clarify the su...

journal_title：Journal of thoracic disease

authors： Wen CT,Fu JY,Wu CF,Hsieh MJ,Liu YH,Wu YC,Tsai YH,Wu CY

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The tetraspanin KAI1/CD82 was identified as a tumor metastasis suppressor that down-regulated in malignant progression of lung cancer. However, the underlying mechanism of anti-metastasis role of KAI1 in lung cancer is hardly known. In this paper, we sought to study the function and regulatory mechanism of K...

journal_title：Journal of thoracic disease

authors： You J,Chang R,Liu B,Zu L,Zhou Q

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) may play an important role in organ development, cell differentiation, apoptosis, proliferation, cell growth regulation and act as tumor suppressor genes or proto-oncogenes. Single nucleotide polymorphisms (SNPs) in miRNAs are considered to be genetic factors to influence the susceptibilit...

journal_title：Journal of thoracic disease

authors： Ren YG,Zhou XM,Cui ZG,Hou G

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:The analysis of lung artefacts has gained increasing importance as markers of lung pathology. B-line artefact (BLA), caused by a reverberation phenomenon, is the most important lung artefact. In this review, we discuss the current role of BLA in pneumology and explore open questions of the published consensu...

journal_title：Journal of thoracic disease

authors： Dietrich CF,Mathis G,Blaivas M,Volpicelli G,Seibel A,Wastl D,Atkinson NS,Cui XW,Fan M,Yi D

更新日期：2016-06-01 00:00:00

abstract：:Bioresorbable vascular scaffolds (BVS) represent a disruptive technology that has caused a new revolution in interventional cardiology. BVS appear to be particularly appealing in patients presenting with an acute myocardial infarction (MI). The available evidence on the value of BVS implantation in this challenging sc...

journal_title：Journal of thoracic disease

authors： Alfonso F,Cuesta J,Bastante T,Rivero F,García-Guimaraes M,Alvarado T,Benedicto A,Cortese B,Byrne R,Kastrati A

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Minimally invasive cardiac surgery (MICS) has been more commonly performed due to the reduced amount of bleeding and transfusion and length of hospital stay. We investigated the feasibility of performing MICS using single-lumen endotracheal tube (SLT). METHODS:We conducted a retrospective review of clinical...

journal_title：Journal of thoracic disease

authors： Kim HY,Baek SH,Je HG,Kim TK,Kim HJ,Ahn JH,Park SJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The standard treatment for stage III non-small-cell lung cancer (NSCLC) is still 60 Gy in conventional fractions combined with concurrent chemotherapy; however, the resulting local controls are disappointing. The aim of this study was to compare and assess the feasibility and efficacy of hypofractionated che...

journal_title：Journal of thoracic disease

authors： He J,Huang Y,Chen Y,Shi S,Ye L,Hu Y,Zhang J,Zeng Z

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Intensity modulated radiotherapy (IMRT) is routinely utilized in the treatment of locally advanced non-small cell lung cancer (NSCLC). RTOG 0617 found that overall survival was impacted by increased low (5 Gy) and intermediate (30 Gy) cardiac doses. We evaluated the impact of esophageal-sparing IMRT on cardi...

journal_title：Journal of thoracic disease

authors： Woodford K,Panettieri V,Ruben JD,Senthi S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:According to the present evidences suggesting association between low testosterone level and prediction of reduced exercise capacity as well as poor clinical outcome in patients with heart failure, we sought to determine if testosterone replacement therapy (TRT) improves clinical and cardiovascular condition...

journal_title：Journal of thoracic disease

authors： Wang W,Jiang T,Li C,Chen J,Cao K,Qi LW,Li P,Zhu W,Zhu B,Chen Y

更新日期：2016-05-01 00:00:00

abstract：:The main reasons of emergent conversion during thoracoscopic lobectomy included tumor invasion, hilar lymph node (LN) metastasis, and lymphoid tuberculosis. We presented a video which depicted a three-portal thoracoscopic left upper lobectomy with dissection of large LNs. Severe adhesions between a large LN and the fi...

journal_title：Journal of thoracic disease

authors： Ma L,Mei J,Liu C,Liu L

更新日期：2016-05-01 00:00:00

abstract：:We present a case involving alveolar adenoma (AA) comprising a malignant component. An 83-year-old man was referred with a solitary pulmonary nodule, which was diagnosed as adenocarcinoma (AC) by transbronchial biopsy. Resected specimen after left S1+2 segmentectomy revealed that the tumor comprised two histologically...

journal_title：Journal of thoracic disease

authors： Okada S,Ohbayashi C,Nishimura M,Abe K,Choh S,Shimada J,Inoue M

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:To assess the correlation of WHO histological classification of thymomas and thymic carcinomas (TCs) with prognosis in recently treated patient cohort compared to a historical one from a single institution. METHODS:Retrospective review of clinical charts and histological sections of 241 patients treated dur...

journal_title：Journal of thoracic disease

authors： Zhu L,Zhang J,Marx A,Weiss C,Fang WT

更新日期：2016-04-01 00:00:00

abstract：:Due to its intrinsic characteristics, video assisted thoracic surgery (VATS) lobectomy is currently the recommended surgical approach for early stage lung cancer treatment. The importance of increasing the number of surgeons capable of performing VATS lobectomies is implicit and of utmost importance. In fact, the need...

journal_title：Journal of thoracic disease

authors： Sandri A,Filosso PL,Lausi PO,Ruffini E,Oliaro A

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The aim of this study was to reveal the short-term outcomes of video-assisted thoracoscopic surgery (VATS) segmentectomy without tracheal intubation compared with intubated general anesthesia with one-lung ventilation (OLV). METHODS:We performed a retrospective review of our institutional database of consec...

journal_title：Journal of thoracic disease

authors： Guo Z,Yin W,Pan H,Zhang X,Xu X,Shao W,Chen H,He J

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CRT) with 5-fluorouracil (5-FU) and cisplatin (CDDP) are often associated with significant incidence of toxic effects in elderly patients with esophageal cancer. This phase I trial was designed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of S-1...

journal_title：Journal of thoracic disease

authors： Ji Y,Qiu G,Sheng L,Sun X,Zheng Y,Chen M,Du X

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Plaques with a large necrotic core or lipid pool and thin-cap fibroatheroma manifest as attenuated plaques on intravascular ultrasound (IVUS). Their impact on TIMI grade flow and clinical outcomes remains undefined. We performed a systematic review and meta-analysis to summarize the association between atten...

journal_title：Journal of thoracic disease

authors： Jia R,Nie X,Li H,Zhu H,Pu L,Li X,Han J,Yang D,Meng S,Jin Z

更新日期：2016-03-01 00:00:00

abstract：:Lung cancer invading the superior vena cava (SVC) is a locally advanced condition, for which poor prognosis is expected with conservative treatment alone. Surgical resection of the lesion can rapidly relieve the symptoms and significantly improve survival for some patients. Replacement, repair and partial resection of...

journal_title：Journal of thoracic disease

authors： Xu X,Qiu Y,Pan H,Mo L,Chen H,He J

更新日期：2016-03-01 00:00:00

abstract：:Response monitoring using fluorodeoxyglucose positron emission tomography acquired together with low dose computed tomography (FDG-PET/CT) textural features has potential in targeted treatment with erlotinib in non-small cell lung cancer (NSCLC) patients. Patients with substantial decrease of metabolic activity during...

journal_title：Journal of thoracic disease

authors： van Gool MH,Aukema TS,Sinaasappel M,Valdés Olmos RA,Klomp HM

更新日期：2016-03-01 00:00:00

abstract：:Sleeve resection, a mainstay for centrally-located lung cancer, is a challenging procedure when the preserved lung is impaired. We herein reported a 61-year-old male who underwent right upper sleeve lobectomy for squamous cell carcinoma located at the orifice of the upper bronchus. The tumor invaded the main bronchus....

journal_title：Journal of thoracic disease

authors： Shibano T,Tsubochi H,Endo S,Yamamoto S,Maki M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Sporadic case reports have shown that wedge resection and lobectomy can be performed via nonintubated video-assisted thoracoscopic surgery (VATS) with a single incision. We report the feasibility and safety of nonintubated uniportal VATS for resection of various lung lesions. METHODS:From January 2014 to Ju...

journal_title：Journal of thoracic disease

authors： Hung WT,Hsu HH,Hung MH,Hsieh PY,Cheng YJ,Chen JS

更新日期：2016-03-01 00:00:00

abstract：:Management of pulmonary nodules in terms of diagnosis and intraoperative localization can be challenging, especially in the minimal invasive video-assisted thoracoscopic surgery (VATS) approach, and may be even more difficult with single port VATS with limited access. The ability to localize small lesions intraoperati...

journal_title：Journal of thoracic disease

authors： Zhao ZR,Lau RW,Ng CS

更新日期：2016-03-01 00:00:00

abstract：:Non-malignant and malignant obstruction of the tracheal airway causes significant morbidity and mortality. With increased use of artificial airways, benign and iatrogenic complications are increasing. A tracheal stenosis that is less than 5 cm in length can be resected with end-to-end anastomosis. Longer tracheal lesi...

journal_title：Journal of thoracic disease

authors： Delaere P,Van Raemdonck D

更新日期：2016-03-01 00:00:00

abstract：:Protocols for the management of air leaks are critical aspects in the postoperative course of patients following lung resections. Many investigations in the last decade are focusing on the chest tube modalities or preventative measures, however, little is known about the pathophysiology of air leak and the patient per...

journal_title：Journal of thoracic disease

authors： Pompili C,Miserocchi G

更新日期：2016-02-01 00:00:00

abstract：:Approximately 30% to 50% of patients will develop ischemic mitral regurgitation (MR) after a myocardial infarction, which is a result of progressive left ventricular remodeling and dysfunction of the subvalvular apparatus, and portends a poor long-term prognosis. Surgical treatment is centered on mitral valve repair u...

journal_title：Journal of thoracic disease

authors： Mihos CG,Santana O

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:A clinical trial of extracorporeal membrane oxygenation (ECMO) as an alternative ventilator tool is being performed as a new indication for ECMO. The purpose of this study was to evaluate the feasibility of awake ECMO to increase the success rate of weaning patients from ECMO and ventilator care during treat...

journal_title：Journal of thoracic disease

authors： Yeo HJ,Cho WH,Kim D

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Unilateral video-assisted thoracoscopic (VATS) thymectomy features less operative trauma, improved cosmesis, and similar efficiency compared with transsternal (TS) thymectomy for treatment of patients with myasthenia gravis (MG). Unilateral VATS thymectomy can be easily performed from either side of the thor...

journal_title：Journal of thoracic disease

authors： Xie X,Gan X,Chen B,Shen Z,Wang M,Zhang H,Xu X,Chen J

更新日期：2016-01-01 00:00:00

abstract：:We report a case of video-assisted thoracoscopic surgery (VATS) tracheal resection and carinal reconstruction in a patient with tracheal tumor. The patient presented with adenoid cystic carcinoma (ACC) of the distal trachea, extending along the right main bronchus with carinal invasion. The reconstruction procedure wa...

journal_title：Journal of thoracic disease

authors： He J,Wang W,Li J,Yin W,Xu X,Peng G,Chen Y,He P

更新日期：2016-01-01 00:00:00

abstract：:Congenital pulmonary agenesis is a rare condition with high mortality. Mechanical ventilation in these patients is challenging and there has no such case been reported in the literature. We reported a 61-year-old female with lung agenesis who presented to our hospital with pneumonia and pelvic mass. In the past, she h...

journal_title：Journal of thoracic disease

authors： Yu Y,Zhu C,Qian X,Gao Y,Zhang Z

更新日期：2016-01-01 00:00:00

abstract：:In recent years, serious pollutional haze occurs in the mainland of China thanks to the development of urbanization and industrialization. There is a close relationship between air pollution and the occurrence and development of chronic obstructive pulmonary disease (COPD), but there are some new characteristics in so...

journal_title：Journal of thoracic disease

authors： Wang F,Ni SS,Liu H

更新日期：2016-01-01 00:00:00

abstract：:Accurate determination of the diagnosis and the stage of lung cancer play a critical role to ensure that patients are provided the optimal treatment. However, the process is usually beyond complex. Early studies have suggested lymph nodes (LNs) >1.0 cm in size on computed tomography (CT) are considered as metastatic n...

journal_title：Journal of thoracic disease

authors： Xia Y,Zhang B,Zhang H,Li W,Wang KP,Shen H

更新日期：2015-12-01 00:00:00

abstract：:Peripheral lung nodule evaluation represents a clinical challenge. Given that many nodules will be incidentally found with lung cancer screening following the publication of the National Lung Screening Trial (NLST), the goal is to find an accurate, safe and minimally-invasive diagnostic modality to biopsy the concerni...

journal_title：Journal of thoracic disease

authors： Arias S,Yarmus L,Argento AC

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound...

journal_title：Journal of thoracic disease

authors： Chen CH,Cheng WC,Wu BR,Chen CY,Chen WC,Hsia TC,Liao WC,Tu CY,Shih CM,Hsu WH,Wang KP

更新日期：2015-12-01 00:00:00

abstract：:Temporary mechanical circulatory support (MCS) refers to a group of devices generally used for less than 30 days to maintain adequate organ perfusion by compensating for a failure of the pumping mechanism of the heart. The increased availability and rapid adoption of new temporary MCS strategies necessitate physicians...

journal_title：Journal of thoracic disease

authors： Saffarzadeh A,Bonde P

更新日期：2015-12-01 00:00:00

abstract：:The widespread acceptance of left ventricular assist device (LVAD) implantation in the treatment of heart failure has revolutionized the way end stage heart failure is treated. Advances in LVAD technology combined with a better understanding of patient selection has led to unparalleled survival as well as a reduction ...

journal_title：Journal of thoracic disease

authors： Kilic A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Bronchoplastic and broncho-arterioplastic lobectomy is technically demanding. Present study performed a prognostic analysis of lobectomy patient based on 10-year data in a high-volume center. METHODS:Overall, 161 non-small cell lung cancer (NSCLC) cases underwent bronchoplastic and broncho-arterioplastic lo...

journal_title：Journal of thoracic disease

authors： Zhao LL,Zhou FY,Dai CY,Ren YJ,Jiang GN,Fei K,Chen C

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Presently, the clinical effect of radical video-assisted thoracic surgery (VATS) is equal to that of traditional open chest surgery and has received worldwide recognition of its advantages: less trauma and faster recovery. In the attempt to further the advancement of minimally invasive surgery the operative ...

journal_title：Journal of thoracic disease

authors： Wang W,Peng G,Guo Z,Liang L,Dong Q,He J,Yin W

更新日期：2015-12-01 00:00:00

abstract：:Primitive neuro-ectodermal tumour of the lung is an extremely rare occurrence and we hereby report a case of a neuro-ectodermal tumour of the lung which was proved by immuno-histochemical examination of the resected specimen, and he had a very aggressive pattern of behavior. ...

journal_title：Journal of thoracic disease

authors： Gaude GS,Patil P,Malur P,Annurshetru S

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Hand sewn cervical esophagogastric anastomosis (CEGA) is regarded as preferred technique by surgeons after esophagectomy. However, considering the anastomotic leakage and stricture, the optimal technique for performing this anastomosis is still under debate. METHODS:Between November 2010 and September 2012,...

journal_title：Journal of thoracic disease

authors： Feng F,Sun L,Xu G,Hong L,Yang J,Cai L,Li G,Guo M,Lian X,Zhang H

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Subxiphoid thoracoscopic surgery has been used in various thoracic surgical procedures. The aim of this study is to compare the physiological and inflammatory responses between subxiphoid thoracoscopic surgery and standard transthoracic thoracoscopic surgery for anatomic pulmonary lobectomy in a canine model...

journal_title：Journal of thoracic disease

authors： Wen CT,Chu Y,Wu YC,Hsieh MJ,Liu CY,Liu CC,Ko PJ,Liu YH,Liu HP

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The aim of this study is to evaluate the clinical feasibility and efficacy of video-assisted thoracoscopic surgery (VATS) anatomical pulmonary resection in patients with central lung cancer. METHODS:Between July 2004 and December 2011, 465 patients underwent anatomical pulmonary resection and systematic med...

journal_title：Journal of thoracic disease

authors： Jung HS,Kim HR,Choi SH,Kim YH,Kim DK,Park SI

更新日期：2015-10-01 00:00:00